Jamie Conway (Michael J. Fox) is an aspiring writer and yuppie living in New York City who seeks oblivion in cocaine and the glittery nightclub scene as his life falls apart (his wife leaves him, his mother dies, etc.). With his hard-partying friend Tad Allagash (Kiefer Sutherland) tagging along with him during their nights out, Jamie finds it increasingly difficult to show up every day at his unfulfilling job as a fact checker for a literary Manhattan magazine.